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Pharmacies in Port St. Lucie, FL

40 providers · Updated November 2026

Looking for a pharmacy in Port St. Lucie? Below are local pharmacies ranked by public ratings and review volume, with featured practices shown first. Tap Call to reach an office directly, or open a listing for hours, directions and services.

Sorted by recommended Recommended Top rated

CVS Pharmacy

Pharmacy · Port St. Lucie

● Open now 4.3 ★ (59)

9801 S U.S. Hwy 1, Port St. Lucie

CVS Pharmacy

Pharmacy · Port St. Lucie

● Open now 4.0 ★ (100)

9197 S Federal Hwy, Port St. Lucie

CVS Pharmacy

Pharmacy · St. Lucie West

● Open now 3.9 ★ (78)

1300 St Lucie W Blvd, Port St. Lucie

Frequently asked questions

How many pharmacies are in Port St. Lucie, FL?

Our directory currently lists 40 providers under Pharmacies in Port St. Lucie. Listings are updated regularly — business owners can claim and update their listing for free.

Which pharmacies in Port St. Lucie have the highest ratings?

Based on public review data, highly rated options include Bio-logic CBD Health and Wellness (5.0★, 300 reviews), EASTPORT PHARMACY (4.8★, 176 reviews), CrossTown Pharmacy (4.9★, 147 reviews). Always confirm availability and insurance directly with the office.

How do I choose the right pharmacy in Port St. Lucie?

Check that the provider accepts your insurance, look at recent reviews, confirm office hours and location, and call to ask whether they are accepting new patients. Use the Call and Website buttons on each listing to contact them directly.

Is my business missing from this list?

You can add a health business in the Port St. Lucie area for free using the Add Your Business page.

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